Study of case: Monitoring of the method of decontamination with chlorine dioxide in rooms previously occupied by patients colonized with multidrug-resistant Acinetobacter
DOI:
https://doi.org/10.56294/saludcyt20241162Keywords:
Decontamination, Nosocomial Infection, Chlorine Dioxide, Acinetobacter InfectionsAbstract
Contamination of hospital surfaces by patients colonized with Acinetobacter represents a risk of nosocomial infections. The imperative need to prevent intrahospital transmission and dissemination has prompted the implementation of approved agents with high biocidal capacity and low toxicity. In one hospital, it was documented in real time the safety of decontamination with ClO2 at 60 ppm for 30 minutes in unoccupied inpatient rooms by antimicrobial culture and ATP bioluminescence assays. After decontamination, sampling of surfaces occupied by patients colonized with Acinetobacter, no viable culturable spores or metabolic activity was reported. At follow-up, previous and subsequent patients did not develop Acinetobacter infections, and no sign of microbiological contamination was observed after room decontamination. These results suggest that ClO2 can be used as a safe and economical antimicrobial agent with feasibility for integration into medical practices
References
1. Richet H, Fournier PE. Nosocomial Infections Caused by Acinetobacter baumannii A Major Threat Worldwide. Infect Control Hosp Epidemiol. 2006;27(7):645–6.
2. Shelanah F, Gray T, Gottlieb T. Healthcare-acquired infections: prevention strategies. Intern Med J. 2017;47(12):1341–51.
3. Chemaly RF, Simmons S, Dale C, Ghantoji SS, Rodriguez M, Gubb J, et al. The role of the healthcare environment in the spread of multidrug-resistant organisms: update on current best practices for containment. Ther Adv Infect Dis. 2014;2(3-4):79–90.
4. Noszticzius Z, Wittmann M, Kály-Kullai K, Beregvári Z, Kiss I, Rosivall L, et al. Chlorine Dioxide Is a Size-Selective Antimicrobial Agent. PLoS One. 2013;8(11):e79157.
5. Dancer SJ. How do we assess hospital cleaning? A proposal for microbiological standards for surface hygiene in hospitals. J Hosp Infect. 2004;56(1):10–5.
6. Moore G, Smyth D, Singleton J, Wilson P. The use of adenosine triphosphate bioluminescence to assess the efficacy of a modified cleaning program implemented within an intensive care setting. Am J Infect Control. 2010;38(8):617–22.
7. Morino H, Futatsukame M, Miura T, Shibata T. Effect of extremely low-concentration gaseous chlorine dioxide against surface Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii in wet conditions on glass dishes. BMC Res Notes. 2020;13(1):69.
8. Hinenoya A, Awasthi SP, Yasuda N, Shima A, Morino H, Koizumi T, et al. Chlorine Dioxide is a Better Disinfectant than Sodium Hypochlorite against Multi-Drug Resistant: Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii. Jpn J Infect Dis. 2015;68(4):276–9.
9. Espinal P, Martí S, Vila J. Effect of biofilm formation on the survival of Acinetobacter baumannii on dry surfaces. J Hosp Infect. 2012;80(1):56–60.
10. Sanna T, Dallolio L, Raggi A, Mazzetti M, Lorusso G, Zanni A, et al. ATP bioluminescence assay for evaluating cleaning practices in operating theatres: applicability and limitations. BMC Infect Dis. 2018;18(1):583.
Published
Issue
Section
License
Copyright (c) 2024 Manuel Aparicio-Alonso, Alma Guadalupe Avalos-Contreras, Verónica Torres-Solórzano (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.
