Peritoneal Dialysis in Newborns with Cardiac Surgery AKI
DOI:
https://doi.org/10.56294/saludcyt20241316Keywords:
Peritoneal Lavage, Cardiac Surgery, Acute Kidney Injury, Newborns, Neonatal Intensive CareAbstract
This retrospective study evaluates the efficacy of peritoneal dialysis (PD) in mitigating acute kidney injury (AKI) associated with cardiac surgery in newborns. We analyzed data from 120 neonates up to 28 days old who developed AKI post-cardiac surgery and required PD. Statistical analysis was performed using SPSS 26. Results indicated that PD patients were predominantly male (p = 0,007) with an average age of 12,87 days versus 9,32 days (p = 0,015), and an average weight of 3,06 kg compared to 2,76 kg (p = 0,040). Multivariate regression highlighted age (OR = 1,083, p = 0,032), cardiopulmonary bypass duration (OR = 1,081, p = 0,030), and RACHS-1 scores (OR = 4,785, p = 0,037) as significant predictors of PD initiation. Among PD patients, non-survivors had an average age of 10,31 days versus 18,00 days for survivors (p = 0,045), and an average weight of 2,94 kg versus 3,54 kg (p = 0,040). Non-survivors also had shorter cardiopulmonary bypass times (33,63 minutes versus 50,60 minutes, p = 0,036) and aortic cross-clamp times (22,77 minutes versus 26,50 minutes, p = 0,015). Multivariate analysis also showed that younger age (OR = 0,927, p = 0,009), lower weight (OR = 0,597, p = 0,006), higher RACHS-1 scores (OR = 0,432, p = 0,002), longer bypass (OR = 0,969, p = 0,001), and longer cross-clamp times (OR = 0,871, p = 0,007) predicted decreased survival. PD benefits include reduced AKI severity and enhanced survival, particularly in complex cases, despite an increased sepsis risk
References
1. Yuan SM. Acute Kidney Injury after Cardiac Surgery: Risk Factors and Novel Biomarkers. Braz J Cardiovasc Surg. 2019;34(3):352-360. doi:10.21470/1678-9741-2018-0212
2. Alimukhamedov U. Acute renal failure in newborns in the practice of a pediatrician of the future. Futurity Medicine. 2022;1(4):19-29. doi:10.57125/FEM.2022.12.30.02
3. Smokova L, Zhylin M, Mendelo V, Kyrylishyna M, Danilova O. Socio-Psychological Factors in the Development of Emotional Intelligence of Drug Addicts. Int J Stat Med Res. 2023;12:33-42. doi:10.6000/1929-6029.2023.12.05
4. Stepanova N. Oxalate Homeostasis in Non-Stone-Forming Chronic Kidney Disease: A Review of Key Findings and Perspectives. Biomedicines 2023, Vol 11, Page 1654. 2023;11(6):1654. doi:10.3390/BIOMEDICINES11061654
5. Iastremska O, Tryfonova O, Mantaliuk O, Baranets H. The impact of strategic decisions on the future development of organisations and economic dynamics. Futurity Economics&Law. 2023;3(4):117-134. doi:10.57125/FEL.2023.12.25.08
6. Maraieva U. On the formation of a new information worldview of the future (literature review). Futurity Philosophy. 2022;1(1):18-29. doi:10.57125/FP.2022.03.30.02
7. Pothen C, Baby B, Ashokan A, Chacko C, Shenoy P, Nandakumar UP. Drug Usage Pattern in Chronic Kidney Disease patients undergoing maintenance Hemodialysis. Res J Pharm Technol. 2019;12(10):5024-5028. doi:10.5958/0974-360X.2019.00872.2
8. Jasim RH, Hussein KM. Level of Cellular Damage of patients with renal Failure during Dialysis. Res J Pharm Technol. 2021;14(1):103-108. doi:10.5958/0974-360X.2021.00019.6
9. Alaraj M. The effects of Amlodipine and Propranolol on Haemodialysis Efficiency in End-Stage Renal Failure patients. Res J Pharm Technol. 2022;15(10):4343-4347. doi:10.52711/0974-360X.2022.00728
10. Ammor S, Abidli Z, Amri A, et al. Application of the Dijon Physical Activity Score in Chronic hemodialysis patients. Res J Pharm Technol. 2020;13(10):4725-4730. doi:10.5958/0974-360X.2020.00832.X
11. Joudah MT, Saleh SM, Joudah WT, Joudah MT. Biochemical Investigation to Determine the Factors Involved in Renal Failure Formation for Dialysis Patients. Res J Pharm Technol. 2021;14(12):6275-6280. doi:10.52711/0974-360X.2021.01085
12. Mohammed RB, Mohammed MM. Potential role of Niacin as Adjuvant to Sevelamer on Serum levels of Inorganic phosphorus, Calcium and Calcium-phosphorus product in Hemodialysis patients with Hyperphosphatemia. Res J Pharm Technol. 2022;15(5):2158-2162. doi:10.52711/0974-360X.2022.00358
13. Naik G, Ligade V, Prasad S, Guddattu V, Sreedhar D. Healthcare schemes for Hemodialysis patients in India: An Overview and Utilization in selected hospitals. Res J Pharm Technol. 2022;15(10):4382-4388. doi:10.52711/0974-360X.2022.00735
14. Pothen C, Baby B, Ashokan A, Chacko C, Shenoy P, Nandakumar UP. Drug Usage Pattern in Chronic Kidney Disease patients undergoing maintenance Hemodialysis. Res J Pharm Technol. 2019;12(10):5024-5028. doi:10.5958/0974-360X.2019.00872.2
15. Komal Kumar N, Vigneswari D. Hepatitis- Infectious Disease Prediction using Classification Algorithms. Res J Pharm Technol. 2019;12(8):3720-3725. doi:10.5958/0974-360X.2019.00636.X
16. Thomas A, Jacob JS, Abraham M, Thomas BM, Ashok P. Assessment of Acute complications and Quality of Life in Hemodialysis patients with Chronic Kidney Disease. Res J Pharm Technol. 2021;14(5):2671-2675. doi:10.52711/0974-360X.2021.00471
17. Sayed R. Strategic Integration of Business Analytics in Innovation Management: Framework for Sustainable Growth. Futurity of Social Sciences. 2023;1(1):51-66. doi:10.57125/FS.2023.03.20.04
18. Aoun B, Daher GA, Daou KN, et al. Acute Kidney Injury Post-cardiac Surgery in Infants and Children: A Single-Center Experience in a Developing Country. Front Pediatr. 2021;9:637463. doi:10.3389/FPED.2021.637463
19. Shi S, Fan J, Shu Q. Early prediction of acute kidney injury in neonates with cardiac surgery. World Journal of Pediatric Surgery. 2020;3(2):e000107. doi:10.1136/WJPS-2019-000107
20. Kumar Sahu M, Bipin C, Arora Y, et al. Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients. Indian J Crit Care Med. 2019;23(8):371. doi:10.5005/JP-JOURNALS-10071-23221
21. Xing Y, Sheng K, Liu H, et al. Acute peritoneal dialysis is an efficient and reliable alternative therapy in preterm neonates with acute kidney injury. Transl Pediatr. 2021;10(4):89399-89899. doi:10.21037/TP-20-469
22. Neumayr TM, Alge JL, Afonso NS, Akcan-Arikan A. Acute Kidney Injury after Pediatric Cardiac Surgery. Pediatric Critical Care Medicine. 2022;23(5):E249-E256. doi:10.1097/PCC.0000000000002933
23. Öktener Anuk E, Erdoğan İ, Özkan M, Baskin E, Varan B, Tokel NK. Evaluation of acute kidney injury after surgery for congenital heart disease in neonates: a tertiary hospital experience. The Journal of Maternal-Fetal & Neonatal Medicine. 2022;35(25):9496-9503. doi:10.1080/14767058.2022.2044774
24. Flores S, Loomba RS, Elhoff JJ, et al. Peritoneal Dialysis Vs Diuretics in Children After Congenital Heart Surgery. Ann Thorac Surg. 2019;108(3):806-812. doi:10.1016/J.ATHORACSUR.2019.03.066
25. Kellum JA, Romagnani P, Ashuntantang G, Ronco C, Zarbock A, Anders HJ. Acute kidney injury. Nature Reviews Disease Primers 2021 7:1. 2021;7(1):1-17. doi:10.1038/s41572-021-00284-z
26. Sharma A, Chakraborty R, Sharma K, Sethi SK, Raina R. Development of acute kidney injury following pediatric cardiac surgery. Kidney Res Clin Pract. 2020;39(3):259. doi:10.23876/J.KRCP.20.053
27. Loomba RS, Villarreal EG, Bronicki RA, Flores S. Peritoneal dialysis during congenital heart surgery admissions: insights from a large database. Cardiol Young. 2020;30(4):451-455. doi:10.1017/S1047951120000141
28. Kumar Sahu M, Bipin C, Arora Y, et al. Peritoneal Dialysis in Pediatric Postoperative Cardiac Surgical Patients. Indian J Crit Care Med. 2019;23(8):371. doi:10.5005/JP-JOURNALS-10071-23221
29. Cullis B. Peritoneal dialysis for acute kidney injury: back on the front-line. Clin Kidney J. 2023;16(2):210-217. doi:10.1093/CKJ/SFAC201
30. Cullis B, Al-Hwiesh A, Kilonzo K, et al. ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 update (adults). Peritoneal Dialysis International. 2021;41(1):15-31. doi:10.1177/0896860820970834/ASSET/IMAGES/LARGE/10.1177_0896860820970834-FIG1.JPEG
31. Neumayr TM. Peritoneal dialysis in infants after cardiopulmonary bypass: Is sooner better than later? Pediatric Critical Care Medicine. 2019;20(2):197-198. doi:10.1097/PCC.0000000000001823
32. Yuan SM. Acute kidney injury after pediatric cardiac surgery. Pediatr Neonatol. 2019;60(1):3-11. doi:10.1016/J.PEDNEO.2018.03.007
33. Parolin M, Ceschia G, Vidal E. New perspectives in pediatric dialysis technologies: the case for neonates and infants with acute kidney injury. Pediatr Nephrol. 2024;39(1):115. doi:10.1007/S00467-023-05933-X
34. Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Medicine 2021 47:11. 2021;47(11):1181-1247. doi:10.1007/S00134-021-06506-Y
35. Tekkarişmaz N, Torun D. Long-term clinical outcomes of peritoneal dialysis patients: 9-year experience of a single centre in Turkey. Turk J Med Sci. 2020;50(2):386. doi:10.3906/SAG-1909-98
36. Lim JH, Kim JH, Jeon Y, et al. The benefit of planned dialysis to early survival on hemodialysis versus peritoneal dialysis: a nationwide prospective multicenter study in Korea. Scientific Reports 2023 13:1. 2023;13(1):1-10. doi:10.1038/s41598-023-33216-w
37. Bassil E, Matta M, El Gharably H, et al. Cardiac Surgery Outcomes in Patients Receiving Hemodialysis Versus Peritoneal Dialysis. Kidney Med. Published online December 9, 2023:100774. doi:10.1016/J.XKME.2023.100774
38. Van den Eynde J, Rotbi H, Gewillig M, Kutty S, Allegaert K, Mekahli D. In-Hospital Outcomes of Acute Kidney Injury After Pediatric Cardiac Surgery: A Meta-Analysis. Front Pediatr. 2021;9:733744. doi:10.3389/FPED.2021.733744/BIBTEX
39. Androsova N. Digital Opportunities for the Development of Inclusive Education in Primary School in Ukraine: A Teacher’s Experience. ELIJ [Internet]. 2023 Mar. 25 [cited 2024 Jun. 27];1(1):4-21. Available from: https://www.el-journal.org/index.php/journal/article/view/1
Published
Issue
Section
License
Copyright (c) 2024 Bekzat Suieubekov, Volodymyr Zhovnir, Anar Sepbayeva, Ainur Yeshmanoca, Nishankul Bozhbanbayeva, Zhanara Buribayeva, Galiya Bazarbekova (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.
