Dengue and malaria coinfection in a traveling patient: Case study

Authors

  • Joshua Culcay Delgado Universidad San Gregorio de Portoviejo, Cátedra de Microbiología Médica. Portoviejo, Ecuador Author https://orcid.org/0000-0002-8433-060X
  • Cindy Giselle Díaz Contino Universidad San Gregorio de Portoviejo, Dirección de Investigación. Portoviejo, Ecuador Author https://orcid.org/0000-0001-6949-406X
  • Saul Alexander Coloma Vera Universidad San Gregorio de Portoviejo, Estudiante de medicina. Portoviejo, Ecuador Author https://orcid.org/0009-0007-3931-2211
  • Dalila Auxiliadora Muñoz Rodríguez Hospital de Especialidades Portoviejo, Jefatura de Medicina Interna. Portoviejo, Ecuador Author
  • Beatriz Ariza Ayala Hospital Universitario San Ignacio, Grupo de Investigación en Ciencias de Laboratorio Clínico, Hospital Universitario San Ignacio; Grupo de Investigación de Enfermedades Infecciosas. Bogotá, Colombia Author https://orcid.org/0000-0001-8650-5285

DOI:

https://doi.org/10.56294/saludcyt2024.596

Keywords:

arbovirus, vector-borne diseases, traveler's infections, malaria, dengue

Abstract

Introduction: Dengue and malaria are two prevalent diseases in the tropics, transmitted by vectors, and cause different morbidity and fatality rates. However, coinfection of dengue and malaria is relatively rare but clinically significant, since both diseases can have severe manifestations and their coexistence complicate diagnosis and treatment. 
Clinical Case: The clinical case of a male patient, 32 years old, resident in Angola, who entered Ecuador twenty-one days prior to the onset of symptoms, with no history, was hospitalized for unquantified temperature rise, myalgia, arthralgia and fatigue. His clinical picture is exacerbated with abdominal pain in the right upper quadrant and generalized rash, BP: 105/58 mmHg, HR: 108 bpm, RR: 18 rpm, pulse oximetry 98%, T°: 38°C, dry oral mucosa, expansibility of the decreased chest, dysrhythmic heart, no murmurs, painful abdomen, absent fluid sounds, extremities without edema. The rapid antigen test performed was positive for Plasmodium falciparum, thick smear positive for Plasmodium falciparum. 
Discussion: The simultaneous treatment of malaria and dengue required careful monitoring of warning signs and possible complications; collaboration between health professionals from Ecuador and Angola was necessary for the successful management and handling of the patient.
Conclusions: Documentation of such cases should influence health policies and the planning of preventive strategies, such as vaccination, vector control, and preventive education of travelers before visiting endemic areas.

References

Informe mundial sobre la malaria 2023 [Internet]. Ginebra: Organización Mundial de la Salud; 2023 [citado 2024 Jul 11]. Disponible en: https://www.who.int/es/teams/global-malaria-programme/reports/world-malaria-report-2023

Informe anual de la OMS sobre el paludismo pone de relieve la creciente amenaza del cambio climático [Internet]. Ginebra: Organización Mundial de la Salud; 2023 [citado 2024 Jul 11]. https://www.who.int/es/news/item/30-11-2023-who-s-annual-malaria-report-spotlights-the-growing-threat-of-climate-change

Gaceta de Enfermedades Vectoriales 2024 [Internet]. Ecuador: Ministerio de Salud Pública; 2024 [citado 2024 Jul 11]. Disponible en: https://www.salud.gob.ec/wp-content/uploads/2024/02/GACETA-ENF-VECTORIALES-SE-1-2024.pdf

Informe de la situación epidemiológica del dengue en las Américas [Internet]. Pan American Health Organization, 2024 [citado 2024 Jul 11]. Disponible en: https://www.paho.org/plisa

Dengue – La Región de las Américas [Internet]. World Health Organization, 2024 Health Organization. https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON475

Gautam A, Aryal U, Bhandari S, Pradhan S, Bhattarai U, Mishra A, et al. Dengue and malaria coinfection: The first case report in Nepal. Oxf Med Case Reports. 2022[citado 2024 Jul 11], (3):103–5. https://doi.org/10.1093%2Fomcr%2Fomac022

Gebremariam TT, Schalling HDFH, Kurmane ZM, Danquah JB. Increasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies. Malar J.2023[citado 2024 Jul 11] ;22(1). https://doi.org/10.1186/s12936-023-04723-y

Dulcey L, Theran J, Parales R, Caltagironne R. Descripción de la coinfeccion Malaria Dengue a proposito de un caso clinico primera descripción en el IAHULA. Acta Bioclínica. 2022[citado 2024 Jul 11]; 12(24):158–69. https://dialnet.unirioja.es/servlet/articulo?codigo=8929565

Shetty NP, Shetty PS. Epidemiology of disease in the tropics. Manson's Tropical Diseases, 19 [citado 2024 Jul 11]. https://doi.org/10.1016%2FB978-1-4160-4470-3.50007-0

Yuan K, Chen Y, Zhong M, Lin Y, Liu L. Risk and predictive factors for severe dengue infection: A systematic review and meta-analysis. PLoS One. 2022 [citado 2024 Jul 11];17(4)11. https://doi.org/10.1371%2Fjournal.pone.0267186

Buss I, Genton B, D’Acremont V. Aetiology of fever in returning travellers and migrants: a systematic review and meta-analysis. J Travel Med. 2020 [citado 2024 Jul 11]; 27(8) doi:10.1093/jtm/taaa207.

Salam N, Mustafa S, Hafiz A, Chaudhary AA, Deeba F, Parveen S. Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review. BMC Public Health. 2018[citado 2024 Jul 11]; 18:1-20. doi:10.1186/s12889-018-5626-z.

Desmet S, Henckaerts L, Ombelet S, Damanet B, Vanbrabant P. Imported diseases in travellers presenting to the emergency department after a stay in a malaria-endemic country: a retrospective observational study. Trop Dis Travel Med Vaccines. 2023[citado 2024 Jul 11]; 9(1):3. doi:10.1186/s40794-023-00190-0.

Kitro A, Ngamprasertchai T, Srithanaviboonchai K. Infectious diseases and predominant travel-related syndromes among long-term expatriates living in low-and middle-income countries: a scoping review. Trop Dis Travel Med Vaccines. 2022[citado 2024 Jul 11]; 8(1):11. doi: 10.1186/s40794-022-00168-4.14.

Epelboin L, Hanf M, Dussart P, Ouar-Epelboin S, Djossou F, Nacher M, et al. Is dengue and malaria co-infection more severe than single infections? A retrospective matched-pair study in French Guiana. Malar J. 2012[citado 2024 Jul 11]; 11:1-8. doi: 10.1186/1475-2875-11-142.

Kotepui M, Kotepui KU. Prevalence and laboratory analysis of malaria and dengue co-infection: a systematic review and meta-analysis. BMC Public Health. 2019[citado 2024 Jul 11]; 19:1-12. doi: 10.1186/s12889-019-7489-3.

Downloads

Published

2024-09-06

How to Cite

1.
Culcay Delgado J, Díaz Contino CG, Coloma Vera SA, Muñoz Rodríguez DA, Ayala BA. Dengue and malaria coinfection in a traveling patient: Case study. Salud, Ciencia y Tecnología [Internet]. 2024 Sep. 6 [cited 2024 Oct. 14];4:.596. Available from: https://sct.ageditor.ar/index.php/sct/article/view/596