Impact of alcohol consumption during pregnancy on fetal development and diagnosis of FASD

Authors

DOI:

https://doi.org/10.56294/saludcyt2024.529

Keywords:

prenatal alcohol exposure, fetal alcohol syndrome, neuropsychological disorders, prevention and diagnosis

Abstract

The study was conducted to determine the effects of alcohol consumption during pregnancy on fetal development. A descriptive approach was adopted and an exhaustive documentary and bibliographic review was conducted to analyze the impact of alcohol on the fetus, based on the existing scientific literature. The research focused on the analysis of 11 articles selected from 20 initially reviewed, without collecting primary data. Inductive and deductive methods were used to establish connections between prenatal alcohol exposure and various disorders, including fetal alcohol syndrome and other congenital defects. The results revealed a significant association between prenatal alcohol exposure and an increase in the prevalence of neuropsychological disorders, such as attention deficit hyperactivity disorder, autism spectrum disorder, intellectual disability, and learning disorders. This association was observed in populations from various regions, including Latin America, underlining the global dimension of the problem. In addition, alcohol consumption during pregnancy negatively affected the physical growth and cardiovascular parameters of the fetus. The findings highlighted that fetal alcohol syndrome is often underdiagnosed due to the lack of specific biomarkers and distinctive facial features. Improving prevention and diagnosis strategies through increased education on the risks of alcohol consumption during pregnancy is recommended. Future research was suggested to focus on reducing the associated stigma and improving access to diagnostic and treatment services, considering social and cultural factors

References

1. Lopes C de S. Consumo de alcohol durante el embarazo:¿ resultado de una trayectoria de consumo de riesgo? [Internet]. Vol. 39, Cadernos de Saúde Pública. SciELO Brasil; 2023. p. e00129523. Available from: https://www.scielo.br/j/csp/a/CMf867LNBBQjgf5bCYJp5Nn/?lang=es

2. Cabezas LB, Rodríguez CM, del Fresno Serrano MÁ. Consumo de alcohol durante el embarazo. Rev Sanit Investig [Internet]. 2022;3(2):40. Available from: https://enfispo.es/servlet/articulo?codigo=8340827

3. Lichtenberger A, Peltzer RI, Conde K, Santángelo PR, Cremonte M. Normas sociales y consumo de alcohol en mujeres embarazadas de la Argentina. Interdisciplinaria [Internet]. 2020;37(2):227–38. Available from: http://www.scielo.org.ar/scielo.php?pid=S1668-70272020000200227&script=sci_arttext

4. Lliteras IB, Martínez AG. Principales causas de las malformaciones congénitas. Rev CENIC Ciencias Biológicas [Internet]. 2023;54:30–6. Available from: https://www.redalyc.org/journal/1812/181276105009/181276105009.pdf

5. Popova S, Lange S, Shield K, Burd L, Rehm J. Prevalence of fetal alcohol spectrum disorder among special subpopulations: a systematic review and meta‐analysis. Addiction [Internet]. 2019;114(7):1150–72. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/add.14598

6. DeJong K, Olyaei AMY, Lo JO. Alcohol use in pregnancy. Clin Obstet Gynecol [Internet]. 2019;62(1):142–55. Available from: https://journals.lww.com/clinicalobgyn/abstract/2019/03000/alcohol_use_in_pregnancy.17.aspx

7. Tobiasz AM, Duncan JR, Bursac Z, Sullivan RD, Tate DL, Dopico AM, et al. The effect of prenatal alcohol exposure on fetal growth and cardiovascular parameters in a baboon model of pregnancy. Reprod Sci [Internet]. 2018;25(7):1116–23. Available from: https://journals.sagepub.com/doi/abs/10.1177/1933719117734317

8. Riley EP, Infante MA, Warren KR. Fetal alcohol spectrum disorders: an overview. Neuropsychol Rev [Internet]. 2011;21:73–80. Available from: https://www.nature.com/articles/s41572-023-00420-x

9. Córdoba García R, Camarelles Guillem F, Muñoz Seco E, Gómez Puente JM, San José Arango J, Ramírez-Manent JI, et al. Recomendaciones sobre el estilo de vida. Actualización PAPPS 2022. Aten primaria [Internet]. 2022;54(Suppl 1):102442. Available from: https://docusalut.com/handle/20.500.13003/18712

10. Maya-Enero S, Ramis-Fernández SM, Astals-Vizcaino M, García-Algar Ó. Perfil neurocognitivo y conductual del trastorno del espectro alcohólico fetal. In: Anales de Pediatría [Internet]. Elsevier; 2021. p. 208-e1. Available from: https://www.sciencedirect.com/science/article/pii/S1695403320305385

11. Landgren M, Svensson L, Strömland K, Andersson Grönlund M. Prenatal alcohol exposure and neurodevelopmental disorders in children adopted from eastern Europe. Pediatrics [Internet]. 2010;125(5):e1178–85. Available from: https://publications.aap.org/pediatrics/article-abstract/125/5/e1178/72530/Prenatal-Alcohol-Exposure-and-Neurodevelopmental

12. González GMS. Trastornos del espectro alcohólico fetal: Fetal alcohol spectrum disorders. LATAM Rev Latinoam Ciencias Soc y Humanidades [Internet]. 2023;4(6):1459–67. Available from: http://latam.redilat.org/index.php/lt/article/view/1566

13. Sans-Fitó A, Solerdelcoll A, Boix-Lluch C, Serra-Amaya C, Serra-Grabulosa JM, Caldú X. Trastorno del espectro alcohólico fetal: Un trastorno del neurodesarrollo infradiagnosticado y de pronóstico incierto. Med (Buenos Aires) [Internet]. 2019;79(1):62–7. Available from: http://www.scielo.org.ar/scielo.php?pid=S0025-76802019000200013&script=sci_arttext

14. Rodríguez YEV, Garayzábal E, Sepúlveda EM. Desempeño lingüístico y comunicativo en población con Trastornos del Espectro Alcohólico Fetal. Un estudio de Caso. Rev Investig en Logop [Internet]. 2024;14(2):5. Available from: https://dialnet.unirioja.es/servlet/articulo?codigo=9582199

15. May PA, Baete A, Russo J, Elliott AJ, Blankenship J, Kalberg WO, et al. Prevalence and characteristics of fetal alcohol spectrum disorders. Pediatrics [Internet]. 2014;134(5):855–66. Available from: https://publications.aap.org/pediatrics/article-abstract/134/5/855/75932/Prevalence-and-Characteristics-of-Fetal-Alcohol?autologincheck=redirected

16. Wozniak JR, Riley EP, Charness ME. Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder. Lancet Neurol [Internet]. 2019;18(8):760–70. Available from: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(19)30150-4/abstract

17. Williams JF, Smith VC. Fetal alcohol spectrum disorders. Pediatrics [Internet]. 2015;136(5). Available from: https://publications.aap.org/pediatrics/article/136/5/e20153113/33770/Fetal-Alcohol-Spectrum-Disorders

18. Denny L, Coles S, Blitz R. Fetal alcohol syndrome and fetal alcohol spectrum disorders. Am Fam Physician [Internet]. 2017;96(8):515-522A. Available from: https://www.aafp.org/pubs/afp/issues/2017/1015/p515.html

19. Díaz Jiménez M, Vidal Revé S, Ferreiro Hernández L, Díaz Ortiz L, Soler Ortiz I. Cardiopatía congénita y embarazo. Rev Inf Cient [Internet]. 2016;95(1). Disponible en: https://revinfcientifica.sld.cu/index.php/ric/article/view/148

20. Rábago de Ávila M, Márquez Pérez LL, Pérez Ocampo HF, González Bernal VM, Hernández Guerrero F. Narrativa de la experiencia docente en la educación superior ante la presencia de síntomas del burnout en el estado de Nayarit. Dilemas contemp: educ política valores [Internet]. 2023 [cited 2024 Sep 14]; Available from: https://dilemascontemporaneoseducacionpoliticayvalores.com/index.php/dilemas/article/view/3737.

Downloads

Published

2024-12-04

How to Cite

1.
Abril Saltos AJ, Bonilla Ledesma DV, Diaz Ruiz GN, España Aguilera GDL. Impact of alcohol consumption during pregnancy on fetal development and diagnosis of FASD. Salud, Ciencia y Tecnología [Internet]. 2024 Dec. 4 [cited 2025 Jun. 22];4:.529. Available from: https://sct.ageditor.ar/index.php/sct/article/view/529