Two-stage bilateral subthalamotomy for patients with idiopathic Parkinson's disease
DOI:
https://doi.org/10.56294/saludcyt2023578Keywords:
Parkinson's Disease, Subthalamic Nucleus, Radiofrequency Ablation, NeurosurgeryAbstract
Introduction: in the world there is sufficient experience with functional surgery for Parkinson's disease using the subthalamic nucleus approach, but mainly with the use of deep brain stimulation. Less experience exists in the use of ablative methods.
Objective: to evaluate the therapeutic effect, refinement in surgical target localization and safety of bilateral subthalamic subthalamotomy in two surgical times for the treatment of patients with idiopathic Parkinson's disease.
Methods: observational, analytical, cross-sectional study at CIREN (Havana, Cuba) between January 2018 and December 2020, in 10 patients. Variables related to general characteristics of patients and surgeries, therapeutic effect of the procedure, refinement of surgical target localization and safety of surgeries were analyzed.
Results: the motor condition of the patients improved (p < 0,0001) both in the off stage (70,9 %) and on stage (74,7 %). Target localization refinement reduced the number of paths (5,3 ± 2 vs. 3,4 ± 0,5, p = 0,03) and surgical time (87,6 ± 40,7 min vs. 53,6 ± 13,5 min, p = 0,01). A total of 10 adverse events occurred.
Conclusions: the procedure used has a beneficial and safe therapeutic effect on the motor condition of patients with idiopathic Parkinson's disease. The refinement of the localization of the surgical target allows a reduction in the number of paths and the surgical time
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