Effect of physical exercise on the regulation of glycogenesis: a systematic review

Authors

DOI:

https://doi.org/10.56294/saludcyt20251917

Keywords:

Physical exercise, Glycogenesis, Glucose metabolism, Insulin, Physical activity, Metabolic regulation

Abstract

Introduction: physical activity has been shown to be a crucial element in the regulation of glucose metabolism and glycogenesis, processes that are fundamental to maintaining energy homeostasis. The process of glycogenesis, which involves the generation of glucose from non-glucose precursors, is essential under conditions of prolonged fasting and during recovery after physical activity. 
Objective: the purpose of this systematic review is to examine the influence of physical exercise on the regulation of glycogenesis, focusing on research that examines how different types of exercise (aerobic, anaerobic, and resistance) affect this process. 
Method: research published between 2000 and 2023 was reviewed, using renowned scientific databases. 
Results: the findings suggest that physical exercise regulates glycogenesis through hormonal mechanisms, particularly the modulation of insulin, glucagon, and cortisol. 
Conclusion: additionally, variations in the response of glycogenesis based on the intensity and duration of exercise are highlighted. It follows that understanding the role of exercise in the regulation of glycogenesis is essential for the development of therapeutic strategies for the treatment of diabetes and other metabolic conditions.

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Published

2025-08-23

How to Cite

1.
Raffo Babici V, Calderón Cisneros JT, Cortez Suárez LA, Serafín Álvarez DH. Effect of physical exercise on the regulation of glycogenesis: a systematic review. Salud, Ciencia y Tecnología [Internet]. 2025 Aug. 23 [cited 2025 Sep. 3];5:1917. Available from: https://sct.ageditor.ar/index.php/sct/article/view/1917