The Unseen Burden: Relationship Between Burnout and Gastrointestinal Symptoms among Healthcare Providers, Review Article
DOI:
https://doi.org/10.56294/saludcyt20251527Keywords:
Sustainable development goals (SDGs), Burnout, Gastrointestinal symptoms, Good health and wellbeingAbstract
Introduction: Burnout, a syndrome characterized by emotional exhaustion, depersonalization, and reduced personal accomplishment, is highly prevalent among healthcare providers. Concurrently, gastrointestinal (GI) symptoms, such as irritable bowel syndrome (IBS), acid reflux, and functional dyspepsia, are frequently reported in this population.
Objective: This review article aims to synthesize the existing evidence on the relationship between burnout and GI symptoms among healthcare providers, which help to ensure healthy lives and promote well-being (Goal-3 in SDGs).
Results: After a comprehensive search of recent articles, the findings suggest a significant bidirectional relationship between burnout and GI symptoms, with chronic stress and dysregulation of the gut-brain axis playing key roles. Interventions targeting stress reduction and organisational changes may mitigate both burnout and GI symptoms. Further research studies are needed to establish causality and evaluate the effectiveness of targeted interventions. Also, there is a need to ensure inclusive and equitable quality education and promote lifelong learning opportunities for healthcare providers to maintain wellbeing.
Conclusions: The relationship between burnout and GI symptoms among healthcare providers is complex and bidirectional. Chronic stress associated with burnout can lead to the development or exacerbation of GI symptoms, while the presence of GI symptoms can contribute to burnout.
References
1. Marlicz W, Koulaouzidis A, Charisopoulou D, Jankowski J, Marlicz M, Skonieczna-Zydecka K, Krynicka P, Loniewski I, Samochowiec J, Rydzewska G, Koulaouzidis G. Burnout in healthcare–the Emperor’s New Clothes. Gastroenterology Review/Przegląd Gastroenterologiczny. 2023 Jan 1;18(3):274-80.
2. Bridgeman PJ, Bridgeman MB, Barone J. Burnout syndrome among healthcare professionals. The Bulletin of the American Society of Hospital Pharmacists. 2018 Feb 1;75(3):147-52.
3. Dubale BW, Friedman LE, Chemali Z, Denninger JW, Mehta DH, Alem A, Fricchione GL, Dossett ML, Gelaye B. Systematic review of burnout among healthcare providers in sub-Saharan Africa. BMC public health. 2019 Dec;19:1-20.
4. Sharifi M, Asadi-Pooya AA, Mousavi-Roknabadi RS. Burnout among healthcare providers of COVID-19; a systematic review of epidemiology and recommendations. Archives of academic emergency medicine. 2020 Dec 10;9(1):e7.
5. Chemali Z, Ezzeddine FL, Gelaye B, Dossett ML, Salameh J, Bizri M, Dubale B, Fricchione G. Burnout among healthcare providers in the complex environment of the Middle East: a systematic review. BMC public health. 2019 Dec;19:1-21.
6. Kinman G, Dovey A, Teoh K. Burnout in healthcare: Risk factors and solutions, 2023.
7. Razai MS, Kooner P, Majeed A. Strategies and interventions to improve healthcare professionals’ well-being and reduce burnout. Journal of primary care & community health. 2023 May;14:21501319231178641.
8. Zheng Y, Tang PK, Lin G, Liu J, Hu H, Wu AM, Ung CO. Burnout among healthcare providers: Its prevalence and association with anxiety and depression during the COVID-19 pandemic in Macao, China. PloS one. 2023 Mar 16;18(3):e0283239.
9. Woo T, Ho R, Tang A, Tam W. Global prevalence of burnout symptoms among nurses: A systematic review and meta-analysis. Journal of psychiatric research. 2020 Apr 1;123:9-20.
10. Hassan ME, Elsehrawy MG, Eltayeb MM, Ebrahim EE, Abd-Elsalam NA. Burnout and stress among healthcare Workers at Primary Healthcare Centers: the role of COVID-19 pandemic. Int J Biomed. 2022;12:256-64.
11. Salvagioni DA, Melanda FN, Mesas AE, González AD, Gabani FL, Andrade SM. Physical, psychological and occupational consequences of job burnout: A systematic review of prospective studies. PloS one. 2017 Oct 4;12(10):e0185781.
12. Membrive-Jimenez MJ, Gomez-Urquiza JL, Suleiman-Martos N, Velando-Soriano A, Ariza T, De la Fuente-Solana EI, Canadas-De la Fuente GA. Relation between burnout and sleep problems in nurses: a systematic review with meta-analysis. Healthcare 2022 May 21 (Vol. 10, No. 5, p. 954). MDPI
13. Iglesias ME, de Bengoa Vallejo RB. Prevalence and relationship between burnout, job satisfaction, stress, and clinical manifestations in Spanish critical care nurses. Dimensions of Critical Care Nursing. 2013 May 1;32(3):130-7.
14. Barello S, Palamenghi L, Graffigna G. Burnout and somatic symptoms among frontline healthcare professionals at the peak of the Italian COVID-19 pandemic. Psychiatry research. 2020 Aug 1;290:113129.
15. Alzahrani MA, Alamri HA, Alshehri MA, Ayyashi MM, Alqarni SA, Alshehri SH, Alshehri MS, Alqahtani MM, Alasmari NH, Alsabban AM, Alshahrani AS. Assessing the relationship between burnout syndrome and irritable bowel syndrome among medical health providers and medical students in Saudi Arabia. Journal of Medicine and Life. 2023 Feb;16(2):277.
16. Hod K, Melamed S, Dekel R, Maharshak N, Sperber AD. Burnout, but not job strain, is associated with irritable bowel syndrome in working adults. Journal of psychosomatic research. 2020 Jul 1;134:110121.
17. Masihipour B, Mansour-Ghanaei F, Maroufizadeh S, Hassanipour S, Asgharnezhad M, Isanazar A. The Association of Depression and Anxiety Disorders With Gastrointestinal Symptoms Among Nurses. Caspian J Neurol Sci. 2025; 11 (1): 28-37 [Internet]. 2025 Jan 1.
18. Huerta-Franco MR, Vargas-Luna M, Tienda P, Delgadillo-Holtfort I, Balleza-Ordaz M, Flores-Hernandez C. Effects of occupational stress on the gastrointestinal tract. World journal of gastrointestinal pathophysiology. 2013 Nov 15;4(4):108.
19. Howard K, Giblin M, Medina R. The relationship between occupational stress and gastrointestinal illness: A comprehensive study of public schoolteachers. Journal of Workplace Behavioral Health. 2018 Oct 2;33(3-4):260-75.
20. Menekli T, Doğan R, Yıldız E. Relationship between stress perceived and gastrointestinal symptoms in intensive care nurses during COVID-19 pandemic: a cross-sectional study. Athens Journal of Health and Medical Sciences. 2021;8(4):217-30.
21. Lee EY, Mun MS, Lee SH, Cho HS. Perceived stress and gastrointestinal symptoms in nursing students in Korea: A cross-sectional survey. BMC nursing. 2011 Dec;10:1-8.
22. Lin PY, Wang JY, Shih DP, Kuo HW, Liang WM. The interaction effects of burnout and job support on peptic ulcer disease (PUD) among firefighters and policemen. International journal of environmental research and public health. 2019 Jul;16(13):2369.
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Copyright (c) 2025 Mohamed Gamal El-sehrawy, Mohamed A. El-Sakhawy, Ali D. Abousoliman, Samia Eaid Elgazzar (Author)
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The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.
